 | MobiMicrobe® High-throughput Yeast Single Cell RNA-Seq KitThe MobiMicrobe® High-throughput Yeast Single Cell RNA-Seq Kit is designed for use with the MobiNova®-100 High-throughput Single-Cell System, enabling rapid construction of transcriptome sequencing libraries from hundreds to tens of thousands of single yeasts. This kit employs breakthrough bead-based molecular barcoding technology to efficiently capture yeast mRNA molecules, ensuring stable quality and outstanding performance of the constructed libraries. It enables gene expression profiling at the single yeast cell level, providing deep insights into functional and expression differences among individual yeast cells, and revealing their functional, metabolic characteristics, and environmental adaptability. |
Experimental Data & Case
1. Representative Benchmark Data:
A single-cell suspension of Saccharomyces cerevisiae was prepared for microbial single-cell transcriptome analysis. The captured cell number was 8,546, with a median gene count of 929.
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High technical reproducibility & accurate capture of multiple subpopulation features
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Superior data performance
2. Application Case:
Design of the biosensor-dependent coupling system stabilizes the high-synthesis phenotype of cell factory
Nature Communications (IF: 15.7)
Using the MobiMicrobe® Yeast Single Cell RNA-Seq Kit, single‑cell resolution mapping of subpopulation division in growth‑synthesis coupled yeast populations was achieved. It was revealed that coupling does not eliminate heterogeneity but rather confines high‑yield functions to specific subpopulations. Moreover, single‑cell data enabled the discovery of novel synthetic biology targets that are completely overlooked by bulk transcriptome analysis.
Qin L, Yang B, Huang R, Zhang H, Li Q, Li X, Tan Y, Sun W, Jia H, Hu B, Lv B, Li C. Design of the biosensor-dependent coupling system stabilizes the high-synthesis phenotype of cell factory. Nat Commun. 2026 Apr 13.
Experimental Procedures And Principles
Applications
