Microbial single-cell genome sequencing and library preparation system

The MobiNova®-M1’s Microbe-seq integrates advanced microfluidic and barcoding technologies to resolve high-quality genomes from microbial communities at the unprecedented strain level without the loss of detection resolution or species applicability, enabling microbial research to enter the single-cell era.

Single Cell Microbial Kit

MobiMicrobe® single-cell microbial kit, applicable for a variety of samples such as Gram-negative/positive bacteria, providing end-to-end solutions of microbial lysis, whole-genome amplification, gene fragmentation, and library construction to detect the full length of DNA from single microorganisms.


High-throughput and culture-free

  • Obtain tens of thousands of strain-resolved microbial species without culturing

New species and strains at strain-level

  • Identify new species at unprecedented strain-level resolution

High-quality genome assembly

  • Assemble high-quality genome for functional gene and metabolic pathway analyses

Strain-level interactions

  • Examine insights for horizontal gene transfer analyses and host-phage association mechanisms

Technical Principle

Product Specifications

Detectable Sample
Feces, saliva, soil, water, sludge
1 sample per run
Number of cells captured
> 6000 cells captured per run
Fraction reads in cells
> 50%
Genome assembly
Up to hundreds of genomes with high quality (coverage > 90%, contamination < 5%)
Instrument dimensions
Electrical requirement
Operating Environment
19℃~25℃, and 25%~60% humidity


Q: What are the advantages and features of single-cell microbial genomes?
A: First, Microbe-seq is the first-ever technology worldwide to achieve high-throughput single-microbe genomics at strain-level, which can simultaneously balance throughput and accuracy, and therefore has significant advantages for research needs such as mapping microorganisms in specific samples and efficiently discover microbial resources.
Second, Microbe-seq has higher species identification accuracy compared with traditional microbiome detection techniques such as meta genomics. Microbe-seq can be used to examine the insights such as horizonal gene transfer (HGT) between strains and host-phage association mechanisms.
Q: What kind of samples can Microbe-seq be used for?
A: Microbe-seq can be used for a variety of microbial samples, including fecal samples, oral swabs, vaginal swabs, intestinal contents, soil, sludge, aqueous membranes, marine sediments, and other medical, agricultural, industrial, and environmental microbial samples.